Urodynamics

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The Urodynamics Unit at the Bristol Urological Institute, Southmead Hospital is an internationally renowned centre for urodynamics. It is the largest in the UK, performing about 1000 urodynamic studies a year. 

The unit is one of the most research-active centres in urodynamics with a multidisciplinary team including Urologists, Uro-Gynaecologists, Physiotherapists, Clinical Scientists, Nurses and Urodynamic Technicians.

Urodynamic tests

The word ‘urodynamics’ covers a range of tests designed to show how your bladder is working. This leaflet includes:

  • Standard urodynamics.
  • Video urodynamics (X-rays taken).

Both tests are described in this leaflet, but your healthcare team will tell you which test you are having. You will only be referred for urodynamics if the doctor or nurse feels that the test is important in deciding how to manage your symptoms.

You do not have to have the test, but it will help the doctor diagnose the cause of your problem and offer you the best treatment for your symptoms. Currently, there are no alternatives available that will give us the information provided by the test.

Information on how to prepare for your test and what to expect both during and afterwards is given in this leaflet.

Standard urodynamics

You should allow at least 1 hour 15 minutes for the test. You can eat and drink as normal before the test, but we would like you to come with your bladder comfortably full.

If you are currently taking any of the below tablets for your bladder symptoms you will need to stop taking these 7 days before your test unless you have been told otherwise:

  • Vesicare/solifenacin.
  • Regurin/trospium chloride.
  • Detrusitol/tolterodine.
  • Oxybutynin.
  • Betmiga/mirabegron.

Please complete the three day bladder diary and the questionnaires sent with your appointment letter. You must bring both of them with you to the clinic.

Before the test, please let us know:

  • If you have any allergies, especially to latex.
  • If you have any problems with your mobility.
  • If you feel you may have a urine infection. We are unable to perform urodynamics if you have a urine infection and have symptoms (for example foul-smelling urine or a burning sensation when you urinate).

If you are prone to urinary tract infections, please ensure you get your urine checked by your GP surgery five working days before the appointment so that it can be treated before your appointment.

What the urodynamics test involves

After you arrive, a healthcare professional will explain the test to you and ask some questions about the symptoms that you have been experiencing. You can ask any questions you have about the test.

You will then be asked to sign a consent form to make sure that you understand the procedure, the reasons why it is being done and any potential side effects.

In privacy, you will be asked to change and remove the lower half of your clothing (trousers/skirt/underwear). You will be given a hospital gown to change into and once you are on the couch you will be covered with a sheet.

The healthcare professional will also ask you to pass urine into a special toilet (flowmeter). This measures how fast the flow of your urine is and allows us to check you don’t have a urine infection.

After you have done this, the healthcare professional may examine you. This will include an internal examination, with a chaperone present.

During the test

You will be lying on a couch before one or two small tubes

(no more than 3mm in diameter) will be passed into your bladder. Another small tube will be placed into your rectum (back passage). If you do not have a rectum because you have had surgery and have a colostomy or stoma then that can be used, or the vagina can also be used as an alternative.

These tubes allow us to take measurements both inside and outside the bladder. You will then be asked to sit or stand and your bladder will be slowly filled with water through the tube until you feel full. If you are unable to sit or stand then you will remain lying down on the couch.

You will be asked to cough several times during the test to check the tubes are working. You will also be asked a series of questions such as your first desire to pass urine or whether you experience any urgency.

Once your bladder is comfortably full, one of the bladder tubes will be removed. The tube in your rectum and the very tiny tube in your bladder will be left in. You will then be asked to pass urine and the healthcare professionals will leave the room during this time.

After the test

You will be given time to get dressed in privacy after the test and the results will be explained to you. At this point, you will have the opportunity to ask any questions you may have.

A report will be written and a copy will be sent to your GP, the person who referred you, and yourself.

After the test, you may experience some discomfort where the tubes have been for a short time, but this should settle down. We suggest that you drink extra water during the 24 hours after the test to decrease the chances of you developing an infection.

Video urodynamics

Video urodynamics is similar to standard urodynamics (described above please read and follow the ‘before the test’ guidance above), however, we also take X-ray pictures of your bladder. Instead of using salt water to fill your bladder, we use an iodine-based fluid (this allows us to see your bladder on X-ray).

Before the test, please also let us know:

  • If there is any possibility that you are pregnant as we are unable to perform the test if you are. We may also perform a pregnancy test on the day of your appointment.
  • If you are allergic to Iodine.

What the urodynamics test involves

Unlike standard urodynamics, because we need to X-ray your bladder when you pass urine, we have to remain in the room. We are as discreet as possible and stay behind the curtains when possible.

Patient information

As part of routine clinical practice we process and store personal information relating to our service users. We are required to adhere to the legal requirements of the Data Protection Act 1998 and the General Data Protection Regulation to ensure appropriate patient safety and confidentiality, which we take very seriously. We ensure

the personal information we obtain in held, used, transferred and otherwise processed in accordance with applicable data protection laws and regulations.

Patient data used for research purposes helps improve healthcare such as monitoring patient safety, developing new treatment or developing NHS services. If you would like to opt-out of having your information used for further research, please inform your practitioner on the day of the test.

Useful websites for additional information and advice

© North Bristol NHS Trust. This edition published May 2025. Review due May 2028. NBT002646

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Post Exacerbation Pulmonary Rehabilitation

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What is an exacerbation?

When the symptoms of your lung condition suddenly get worse, it is called an exacerbation. This if often treated in hospital as an inpatient or by a change in your medicine (such as steroids or antibiotics).

What is Pulmonary Rehabilitation (PR)?

Pulmonary Rehabilitation (PR) is a course involving individually tailored exercises to help you manage your breathlessness, gradually increase your fitness level, and understand your lung condition more.

Classes are face to face, twice a week, for six weeks. Each session is up to two hours and involves both education and exercise.

Where are the classes?

We run our PR sessions at Cossham Hospital, Kingswood, Bristol. Sirona community team provide classes in various locations including Bradley Stoke Leisure Centre and the Greenway Centre in Southmead.

Your referral will be sent to the nearest location to where you live. You can tell us if you would prefer to go to another location.

Getting to classes: If you do not have your own transport and are unable to use public transport, please ask a member of the team for advice.

Why am I being offered PR now?

When you have an exacerbation, you may become less active. Even when you are starting to feel better, you may still find it harder to do your daily activities. Doctors have found that starting PR within four weeks of being in hospital after an exacerbation can help patients in the following ways:

  • Reduce your chances of going back into hospital.
  • Make it easer to do daily activities like walking, climbing stairs, or getting dressed.
  • Improve your quality of life.
  • Reduce the risk of another exacerbation.
  • Help you get back to how fit you were before going into hospital.
  • Improve your survival.

It is safe for me?

Your healthcare professional will refer you to PR if they feel it is appropriate for you at this time. The pulmonary rehabilitation specialists will then do a full medical review to check you are safe to participate, and to identify any precautions that need to be taken with you.

How do I get referred?

Your doctor, nurse, or physiotherapist may recommend PR while you are in hospital. If you are not sure if you have been referred please call us.

You should expect a phone call within one to two weeks from being referred to talk about the programme and book an assessment.

Please let us know if you have any questions about PR or why you were referred.

You can have the assessment even if your symptoms are worse than usual; the first part of this is normally done on the phone.

What happens at the assessment?

A specialist physiotherapist will arrange a time to call you. The call will include checking:

  • How your lung condition affects your walking and daily activities.
  • Your medical history and medications.

After the phone assessment you will be invited to a face-face assessment. The appointment will involve things like taking your blood pressure, completing a walking test, and filling in some questionnaires. You can bring a relative, friend, or carer with you to the appointment.

Once the PR team are happy that you are safe to participate, you will be given a date to start PR within one to two weeks.

We aim to get you started on PR within one month of your hospital admission as research suggests you get the most benefits by participating sooner.

What happens during the classes?

You will exercise alongside other patients with a lung condition. You will be fully supervised to make sure you are confident, safe, and progressing as you should.

Each two hour class is split into one hour of exercise and up to one hour of education about self-managing your condition. You will be required to attend the sessions twice a week for the six week course duration.

Exercise

The specialist physiotherapist and exercise specialists will design a programme specifically for you. This will be based on your goals, medical history, and physical ability from your assessment.

Your programme will include arm and leg exercises using exercise equipment like dumbbells. It will also include aerobic exercises such as walking or step-ups.

Education

The education sessions are designed to give you tools to better manage your condition. Topics include:

  • Information about how to manage your lung disease.
  • Breathlessness management.
  • Inhaler technique and medications.
  • How to manage a chest infection.
  • Benefits of exercise and how to exercise at home.
  • Managing your sputum.

Who can I contact for more information?

You can contact the Pulmonary Rehabilitation Team (LEEP):

Asthma and Lung UK

Further resources

NHS website

More information about COPD.

Chronic obstructive pulmonary disease (COPD) - NHS

Asthma and Lung UK

More information about COPD.

Chronic obstructive pulmonary disease (COPD) | Asthma + Lung UK

Right Breathe

Information about how to use your inhalers correctly.

RightBreathe

Support to stop smoking

Try the NHS Quit Smoking app, speak to your local pharmacy or GP, or find out about options for support in your area.

Quit smoking - Better Health - NHS

IAPT Talking Therapies

Get help with your mental health through NHS talking therapies.

NHS Talking Therapy | Vita Health Group

Do you have any questions or comments about your care?

If you have any concerns about the service that the nurses or doctors cannot resolve, you can contact our Patient Advice and Liaison Service (PALS).

PALS offer support and assistance for patients and their families. You can also share positive comments with them about your care.

© North Bristol NHS Trust. This edition published May 2025. Review due May 2028. NBT003628

Contact LEEP

The LEEP Team can be contact on 0117 4142010 or via email at leep@nbt.nhs.uk.  Referrals are accepted via emailed LEEP referral form*, on the ICE referral system or at: The LEEP Office, Physiotherapy Department, Cossham Hospital, Lodge Road, Kingswood, Bristol BS15 1LF.  

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Pneumothorax after a lung biopsy: what to do next

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Information for patients with a small pneumothorax after a lung biopsy at North Bristol NHS Trust

You have had a small sample taken of an abnormal area of your lung today, using local anaesthetic and image guidance. 

Following the procedure, you have a small pneumothorax (collapse of the lung). We are happy that you are safe to go home today, but would like you to come back for another chest X-ray in a few days so we can review your lungs. This is to make sure the pneumothorax (lung collapse) is stable, or improving.

When to come back to Gate 18 Radiology Department

We will give you a date and time to come back to Gate 18 for a chest X-ray. 

You can go home after the X-ray and we will phone you with the result. We will tell you what to do next.

If you have any of the following at home today/tonight, you should go to Southmead Emergency Department or call 999:

  • Severe pain when breathing.
  • Difficulty breathing.
  • Coughing up large amounts of blood (tablespoons).
  • Persistent fever (high temperature).

You can remove the dressing after 24 hours. 

If you have any questions following the procedure, please contact the Lung Cancer Nurse Specialists on 0117 414 1900

© North Bristol NHS Trust. This edition published March 2025. Review due March 2028. NBT003634. 

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Image guided lung biopsy (after your procedure)

Regular Off On Imaging Patient Information Lung biopsy (after your procedure)

Information for patients who have had an image guided lunch biopsy at North Bristol NHS Trust.

You have had a small sample taken of an abnormal area of your lung today, using local anaesthetic and image guidance. We have closely monitored you for a few hours, and are happy that you are safe to go home today. You must have someone to take you home after the procedure and stay with you overnight.

Complications immediately after the procedure are uncommon. If you experience any of the following once at home today/tonight, you should go to Southmead Emergency Department or call 999: 

  • Severe pain when breathing.
  • Difficulty breathing.
  • Coughing up large amounts of blood (tablespoons).
  • Persistent fever (high temperature).

If you develop any of the following symptoms over the next few days, please contact your GP:

  • Increased severe pain.
  • Tender swelling.
  • Redness.
  • Fever.

The dressing may be removed after 24 hours. 

If you have any questions following the procedure, please contact the Lung Cancer Nurse Specialists on 0117 414 1900

© North Bristol NHS Trust. This edition published March 2025. Review due March 2028. NBT003634.

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Find out about shared decision making at NBT. 

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Women and Children's Current Research

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The Women and Children’s Research Unit conducts research that aims to improve the care of women and children using Obstetrics and Gynaecology services. This includes pre-conception services through to postnatal care.

The Unit collaborates widely with other disciplines and professions, as well as with women and their companions, to develop ground-breaking research and care, for our patients and throughout the NHS.

Please speak to the person treating you to find out if there is a research study that may be able to help you.

Maternity Studies:

PANDA

Figures from a trial being led by NHS Blood and Transplant and the University of Oxford show one in three expectant mothers will develop anaemia.

It is a condition where the blood produces a lower-than-normal amount of red blood cells and can be linked to stillbirth, postnatal depression and haemorrhages.

The research team is working with maternity wards across the UK to carry out a study by giving pregnant women an iron supplement to see if it helps.

The trial is being funded by the National Institute for Health and Care Research (NIHR) and will involve giving half the mothers taking part one iron supplement a day and the other half a placebo.

Researchers are working with up to 50 maternity wards across the country.

PANDA, is open to women who are in the first 16 weeks of pregnancy with a single baby and women can ask their healthcare professional for more information or ask about taking part.

Prof Simon Stanworth is a consultant haematologist at NHS Blood and Transplant in Oxford and is running the trial.

About the programme - Clinical Trials Unit - NHS Blood and Transplant

Principal Investigator – Dr Christy Burden

Start date - 01/03/2024

Planned end date – 30/08/2026

Local Ref – 5707

Generation Study

The Generation Study is a national research study that will sequence the genomes of 100,000 newborn babies to test for more than 200 rare and treatable genetic conditions. 

Identifying these conditions shortly after a baby is born, rather than when symptoms might appear later in childhood, means families can receive support, monitoring, and treatment much earlier. Early, effective intervention can help to prevent longer term health problems associated with certain conditions, keeping children out of hospital, and helping them live healthier lives. 

The Generation Study, led by Genomics England in partnership with NHS England, will see parents offered whole genome sequencing using blood samples taken from the umbilical cord shortly after birth.

In Bristol, Southmead Hospital (North Bristol NHS Trust) and St Michael’s Hospital (University Hospitals Bristol and Weston NHS Foundation Trust) are among more than 20 hospitals nationally taking part.

Women planning to give birth at home may also take part in the study. Expectant parents will be informed about the Generation study during pregnancy, and if interested, a research midwife will have a detailed conversation with them to decide if they want to take part. Taking part is voluntary and free. Soon after birth, an NHS doctor, nurse, or midwife will check with parents that they are still happy for their baby to be tested, and a blood sample will be taken and sent to a laboratory for whole genome sequencing.    

Results are then reviewed by NHS genomic scientists. The aim is to share results with parents within 28 days if a condition is suspected, or within a few months if no conditions are suspected. 

If a newborn baby is identified as having a treatable childhood condition through the genome sequencing, families and carers will be provided with further NHS testing to confirm a diagnosis and will receive ongoing support and treatment from the NHS. 

The study will also gather genomic data for wider research purposes, allowing a better understanding of rare genetic conditions. It will also potentially pave the way for new diagnostic tools and treatments and improvements in existing therapies.

In addition, the Generation Study will explore the risks and benefits of storing an individual’s genome over their lifetime. This could allow it to be reanalysed later in life if needed, enabling access to new developments in genomics.

For further information on the Generation Study, visit: www.generationstudy.co.uk

Principal Investigator – Dr Christy Burden 

Planned end date – Currently 31/12 2026.

Local Ref – 5527

Pioneer

A team of researchers and clinician are conducting a study of the use of a medication called Pravastatin by pregnant women who have been identified as being at higher risk of their babies being born too early (preterm birth).

Preterm birth is birth that happens before 37 weeks of pregnancy. It affects around seven out of every 100 babies born in the UK. We do not fully understand why some babies are born too early and at present there are few effective treatments to prevent this from happening. Research shows it is likely that early labour may occur in some pregnancies because of inflammation in the mother’s body. Taking a medication that reduces inflammation, such as Pravastatin, could therefore reduce the number of babies being born too early. Pravastatin is a statin, and statins are a group of medicines which are commonly taken to help lower the risk of heart disease and stroke. Statins work by protecting blood vessels and lowering inflammation in the body.

During the past couple of decades, Pravastatin has been used during pregnancy in studies which have investigated whether Pravastatin prevents or treats other problems/complications of pregnancy. In total 1,303 pregnant women took part in these studies, which showed that there were no safety concerns or problems regarding the baby’s development.

In fact, these studies suggested benefits to the baby, as they found evidence that Pravastatin reduced the number of babies born early. This is what PIONEER will now test. Based on this information, we are interested to find out whether treatment with Pravastatin reduces the chance that a woman will give birth early by: 

  • extending the length of pregnancy
  • reducing the risks associated with babies being born too soon. 

We would also like to find out how Pravastatin might work to reduce early birth by looking at blood samples, vaginal swabs, and stool samples taken from pregnant women who take part in the study.

Everyone who takes part in PIONEER will be randomised into one of two groups: one group will take Pravastatin and the other group will take a placebo (a dummy tablet which looks like Pravastatin but does not contain Pravastatin, only an inactive substance). An equal number of pregnant women will be placed in each group. The aim is to have two groups that are as similar as possible at the start of the study, so that the only thing that differs between the groups is whether they receive the Pravastatin or the placebo. This then allows a fair comparison between the two groups to see if there are differences between the groups in the number of babies born early.

For more information, please visit the study website www.bristol.ac.uk/pioneer

Principal Investigator – Dr Sherif Abdel-Fattah

Planned end date – 31/03/2027.

Local Ref - 5406

CoCo90s

Children of the 90s is a group of around 14,500 children born in the Avon area in 1991 and 1992. Scientists have been studying them ever since and are constantly making discoveries that make a difference to lives around the world.

Some now have children of their own, and we want to follow these pregnancies, births and babies. We call this Children of the Children of the 90s, or COCO90s for short. This is the only project we know of that provides scientists with information on three generations, allowing them to study important social and health issues.

If you or your partner are in Children of the 90s and are about to become or are already a parent, we'd love you, your partner and all your children to take part in COCO90s. It doesn’t matter how much or how little you have been involved in Children of the 90s in the past -- this is a new opportunity to be involved in ground-breaking research.

For more information about this study, visit the CoCo90s website.

Project Details
Principal Investigator: Ms Mary Alvarez
Planned end date: Ongoing
Local Ref: 2801

NICU Studies:

POLAR

Aim: This research project compares two ways we may adjust a commonly used treatment, called positive end-expiratory pressure (or PEEP), to help premature babies’ lungs in the first few minutes after birth.  

Recruitment:  80 babies born before 29 weeks of pregnancy.

The POLAR Trial is a large clinical trial, being conducted in 25 hospitals around the world, including Australia, Europe, the United Kingdom and the USA.

​This trial will establish how to best support the fragile lungs of very premature babies born between 23 and 28 weeks of pregnancy immediately after birth.​

We are comparing two approaches to PEEP levels given to preterm babies’ lungs at birth. We will put your baby into one of two groups, static or dynamic PEEP.  

All the babies in the same group receive the same treatment.  The results are later compared to see if one is better. 

For more information, please visit the POLAR study website.                                                                                          

Project Details
Principal Investigator: Dr Charles Roeher
Planned end date: 30/06/2026
Local Ref: 5152

WHEAT

Aim: The WHEAT International trial will compare two different approaches, feeding babies or not feeding babies during blood transfusions, to work out which one is better. 

Recruitment: We are including all babies that are born before 30 weeks of pregnancy. The WHEAT study is an opt-out study.  This means that all babies will take part unless you let a member of the neonatal team that you do not wish your baby to participate. 

Both approaches are standard practice in the UK but we don’t how best to feed babies during blood transfusions – some hospitals and doctors stop feeds while other don’t. 

Some babies who are born early can develop a bowel disease called necrotising enterocolitis (NEC) which can be serious and can have long-term effects on how babies grow and develop. We want to know if feeding babies or not feeding babies while they have a blood transfusion changes the number of babies that get NEC.

WHEAT is taking places in neonatal units across the UK and Canada and will involve about 4,500 babies.

Project Details
Principal Investigator: Dr Daniela Vieten-Kay
Planned end date: 31/12/2026
Local Ref: 5236

neoGASTRIC

Aim: The neoGASTRIC study is looking at whether routinely measuring gastric residual volumes (checking what is in the stomach before feeding) helps babies safely get to full feeds more quickly. We are comparing two ways of caring for babies having tube feeds, both ways are standard care commonly used in neonatal units across the UK.

Recruitment: We are including all babies born 6 or more weeks early (before 34 weeks of pregnancy) who require tube feeding unless there is another medical reason why they should not take part. All babies will be in the study unless you let a member of the neonatal team know that you do not wish your baby to take part.

Some doctors and nurses routinely measure gastric residual volumes because they think it might help tell if the baby is coping with their feeds, and may help identify signs of a serious but rare gut disease called necrotising enterocolitis (NEC). Other doctors and nurses think that routinely measuring gastric residual volumes may not be a good idea because it can be inaccurate and we do not know if it does help to identify necrotising enterocolitis (NEC). It also increases the amount of procedures each baby has, and may be uncomfortable for them. Routinely measuring gastric residual volumes may also lead to feeds being reduced or even stopped, this will delay the time it takes for the baby to reach full feeds and might affect how well they grow. It will also mean a baby will need intravenous nutrition for longer which can lead to potential problems like infections.

In the UK about half of doctors and nurses routinely measure gastric residual volumes and about half don’t – so both approaches are standard treatment. 

The study is being run in more than 30 hospitals in the UK and Australia for about 3 to 4 years. We hope to include over 7000 babies in the study (UK and Australia combined).

Project Details
Principal Investigator: Paula Brock
Planned end date: 31/10/2026
Local Ref: 5298

Gynaecology Studies:

Take Part in Research

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About Research & Development

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Find out more about our research and how we're working to improve patient care.

Contact Research

Research & Development
North Bristol NHS Trust
Level 3, Learning & Research building
Southmead Hospital
Westbury-on-Trym
Bristol, BS10 5NB

Telephone: 0117 4149330
Email: research@nbt.nhs.uk

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FAST MRI DYAMOND study - Stage 1

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FAST MRI DYAMOND Study 

If you are around 50-52 years of age and have just had your first screening mammogram, you may be able to take part in DYAMOND.  Please first read the participant information below and then sign the consent form on the FAST MRI DYAMOND Electronic Participant Consenting site.

Please take the time to watch this short video explaining the study.

Video Transcript

Have you recently received a letter from the NHS breast screening programme inviting you to come for your first screening mammogram?

The NHS provides a breast screening service because early detection of breast cancer saves lives.

The NHS screening programme has been using mammograms to detect cancer since 1988… But still, 30 women die of breast cancer every day in the UK.

The FAST MRI DYAMOND study is looking to see if a new form of MRI scan, called FAST MRI, can pick up aggressive cancers even earlier than mammograms can. 

The NHS already uses breast MRI to detect cancers, but only for women who have a very high likelihood of having breast cancer. For these women, MRI detects breast cancers earlier than mammograms and saves more lives.

The FAST MRI DYAMOND study will be the first UK study to offer a FAST MRI scan to women at normal or average risk, aged 50-52. People invited for their first screening mammogram can take part at 4 NHS breast screening services in England. (BristolCheltenhamSwindonTruroLondon (St George’s & King’s College).

Everyone’s breasts are different, and in addition to how breasts look and feel in real life, they also look different on mammograms.

At age 50-52, breasts can look completely white on mammograms. They can also look completely dark. Both appearances are normal, as are all the different combinations of white and dark in between. These differences are called mammographic density or breast density.

The problem is that breast density can make a small cancer difficult to spot on a mammogram. Breast cancers tend to show as white on mammograms, so you can see how much easier a cancer would be to spot on the dark mammogram on the left than on the white mammogram on the right.

Fortunately, however, FAST MRI works well at detecting small cancers for women of all breast densities. The pink arrow highlights what a cancer, that was completely invisible on the mammogram, looks like on FAST MRI.

Breast screening with mammograms already saves around 1,300 lives each year in the UK by finding cancers that are too small to feel or see. 

FAST MRI could find cancers even earlier for women and our research is designed to find out which women would benefit from breast screening with FAST MRI through finding breast cancer even earlier than mammograms.

We want to find breast cancers earlier because:

  • finding cancer early makes it more likely that treatment will be successful
  • finding cancer early makes it less likely that a mastectomy will be needed
  • finding cancer early makes it more likely that the cancer will be cured.

The only way to discover your breast density is to have a mammogram.

The FAST MRI DYAMOND study wishes to offer a FAST MRI scan to 1000 people who all have average breast density. At age 50-52, four out of every 10 women will have average breast density and could join the FAST MRI DYAMOND Study to have a FAST MRI scan. 

We can only find out whether you can join the study if you give us your contact details and let us know you are happy for us to use your mammogram to measure your breast density.

Research is fundamental to improving treatment and care for patients and the public but it is your choice whether you join the study or not.

If you are having your first screening mammogram and would like to learn more about the FAST MRI DYAMOND study, please fill in a FAST MRI DYAMOND consent to be contacted form, either online or at your mammogram appointment. 

This is the web address of the online form. 

If you would like to ask any questions at all, you will find the telephone number for the nurse from your local research team below this video along with the link to the online form.

Thank you for taking the time to watch this film. Thank you for helping us with this research.

FAST MRI: DYAMOND

Diagnostic Yield study for Average MammOgraphic screeNing Density (DYAMOND)

Stage 1 Participant Information

Finding breast cancers early saves lives. 

We know that the earlier a breast cancer is diagnosed the better the outcomes for that patient. Mammograms (a type of breast x-ray) have been used for many years to check for breast cancers but may not always find cancers early enough to be helpful. We would like to try out a new method of MRI, called FAST MRI.  

It is like MRI scans you may have heard of, or experienced, but takes much less time, about 3-5 minutes, which would make it suitable to offer to many more people.

What is the FAST MRI DYAMOND study ?

DYAMOND will test if a FAST MRI scan can detect cancers not seen on mammogram, in women with average density breasts. 

1,000 women will be invited for a FAST MRI if:

  • they are aged around 50-52
  • they do not have breast implants
  • their mammogram is clear
  • their breast density is “average” (a computer measures this from mammogram images) 

We would like to invite you to take part in Stage 1 of the study, which uses your mammogram images to measure your breast density. If we ind that you are in the 40% of women with "average breast density, then we will contact you again to invite you to join Stage 2 of the study and have a FAST MRI scan.

Who can take part?

Women with “average” breast density and a clear mammogram may be able to have a FAST MRI. To find this out, we are first inviting women to Stage 1 of the DYAMOND study. 

If you agree to take part in Stage 1, we will send your mammogram to the DYAMOND team at the Royal Surrey NHS Foundation Trust so that they can measure your breast density. We won’t send your mammogram to be measured for 10 working days after we receive your consent. This is in case you change your mind about participating. If you do, please let us know. 

The results will then be sent to Warwick Clinical Trials Unit, to be stored. 

If your mammogram is measured as anything other than average breast density, you will be looked after by the screening service, and you won’t be able to take part in this study. This is because we are only inviting people with “average” breast density to have a FAST MRI. If breast density can't be measured due to having breast implants or for other technical reasons, we will unfortunately not be able to invite you to Stage 2.

If your mammogram measurement is in the “average” breast density group, we will look at your mammogram screening results to check if the screening service says you need any further investigations. This is because in this study, we are only inviting people with clear mammograms to have a FAST MRI.

If you do need some further investigations, the screening service will contact you directly. You won’t be able to have the FAST MRI scan as part of this study. Instead, with your consent, we would like to access your screening and medical records to discover the outcome of your investigations. We will do this for up to 3 years after your first mammogram.

If the screening service says your mammogram needs no further investigations and you are in the average breast density group, we will send you information and an invitation to take part in Stage 2 of the study.

Stage 2 of the FAST MRI DYAMOND study involves having a FAST MRI scan.

Agreeing to take part in Stage 1 does not mean you will automatically have a FAST MRI scan. If the Stage 1 density grading shows you are eligible to take part in Stage 2, you will be invited and can then decide whether to take part or not. 

A member of the research team will contact will contact you to give you information about Stage 2. They will discuss the study with you. If you can have the scan and would like to, they will book you a scan appointment. The scan itself takes just 2-5 minutes, but the whole appointment would last up to 45 minutes. 

Do I have to take part?

No, it’s up to you to decide whether to take part. If you do not want a FAST MRI scan or know you cannot have one, then you can let us know you don’t want to take part. Whether or not you choose to take part, be reassured that your clinical care will not be affected. You will still be offered your routine screening mammograms every 3 years until you turn 71.

Further Information about the FAST MRI DYAMOND study

In this study we will use information from you and from your medical records. We will only use information that we need for the research study. We will let very few DYAMOND team members know your name or contact details, and only if they really need it for this study. This includes research staff at Royal Surrey Hospital who are providing the Consent Form website

Everyone involved in this study will keep your data safe and secure. We will also follow all privacy rules.  At the end of the study, we will save some of the data for up to 5 years after the study closes, in case we need to check it and for future research (if you have given us permission). We will make sure no-one can work out who you are from the reports we write. Please contact us on the details below for more information about this. 

This study is run by Dr Lyn Jones (Consultant Radiologist) at the FAST MRI Programme Team at North Bristol NHS Trust and a Consultant Radiologist at your local Hospital.

FAST MRI DYAMOND Consent Website

How do I sign up?

If you have read the patient information above, or have previously read a leaflet given to you in your breast screening mammogram appointment, you can sign up via the FAST MRI DYAMOND Consent Form.

Study Stages

The study is carried out in two stages: Stage 1 assesses breast density, and Stage 2 invites eligible women to have a FAST MRI scan.

Stage 2 information can be read here , including a video about what it’s like to have a FAST MRI scan.

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Opioids

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What is an opioid?

Opioid refers to morphine and ‘morphine type’ medications. They have been used for many years to treat pain.

Examples of mild opioids include codeine, dihydrocodeine, and tramadol. Sometimes these are combined with paracetamol as research has shown they work better together. They include:

  • Codeine and paracetamol (co-codamol).
  • Dihydrocodeine and paracetamol (co-dydramol).
  • Tramadol and paracetamol (Tramacet).

Stronger opioid drugs include morphine, oxycodone, buprenorphine, fentanyl, diamorphine, alfentanil, and methadone. Opioid medicines come in many forms including tablets, capsules, liquids, skin patches, and injections. 

What are opioids used for?

Opioids provide pain relief by mimicking the body’s natural pain relief (endorphins). They are used when the pain is moderate to severe after an operation or accident. They are also used at different stages of illness.

Opioid medicines can help manage some, but not all types of pain, and they will be prescribed by your medical team in hospital or your GP if it is felt they are the best treatment for your pain.

What are the benefits of taking opioids?

Opioid medicines can help manage pain when other medicines are not suitable, or do not provide enough pain relief. They may help reduce your suffering or distress, and may improve your ability to function physically and socially. They may also allow you to sleep and eat better. 

What are the usual doses of opioids and how should I take them?

The correct dose of any medicine is the lowest dose that produces a noticeable benefit. It is unusual to get complete relief of pain from opioids.

However, it is important to find the most effective dose for you to reduce your pain. The amount needed to control pain varies between people. There is no standard dose of opioid.

Pain is a very personal experience

It is important to understand that the medication/opioids prescribed for your pain may not completely stop your pain – this is normal. The aim of these opioids is to make pain manageable, so you are able to carry out normal daily activities.

You will usually start with a low dose and gradually build up until you find the dose that helps with your pain. The doses can be changed, and other pain medicines can be trialed so your pain is kept under control. Your doctor may try more than one kind of opioid if one type is not right for you.

It is important to control background pain, which is constant and continuous, so you will take a dose at a regular time each day to prevent the pain building up again.

You may have additional medicine for breakthrough pain, which is a sudden, intense pain in addition to the background pain. This will be a short acting preparation (“immediate release”). This acts quickly but usually wears off within a few hours.

It is important to take your pain medicines as they are prescribed.

What if I forget or miss a dose?

If it is almost time for your next dose, skip the missed dose and take your medication as normal (you must leave the prescribed number of hours between doses).

Never take two doses together.

What if the opioids do not control my pain?

If you are using opioids but are still in pain, the opioids are not effective for your pain control and should be stopped by your doctor. Please seek medical advice on weaning opioids if they are not helping to manage your pain- they should not just be stopped.

  • Morphine/morphine equivalent medication doses that are 120mg or above per day (24 hour period) greatly increase the risk of harm caused to your body. Research shows there is no increased benefit to pain control above this 120mg total dose.

If you have significant pain after surgery and are sent home with an opioid prescription, it should be limited to a small amount. If you do take opioids, take them only for a day or two, three days at most. Your pain will improve significantly within a few days whether you take opioids or not.

Can I take this medicine long-term?

While opioids can have a positive effect for some people living with long-term pain, research shows that opioids have little to no benefit for nerve pain.

Taking opioids long term can have serious consequences when they are not providing enough benefit or are being taken not as prescribed. It is important to consider the risks and benefits of continued opioid therapy with your prescriber on a regular basis.

Recent medical research suggests that the risks to your health increase significantly when taking prescribed opioids at high doses for a long period of time. Health risks include accidental overdose or even death.

What are the possible side effects of opioids?

When you first start taking opioids you can experience some side effects, which usually stop after a few days. These include:

  • Feeling dizzy.
  • Feeling sick (nausea).
  • Being sick (vomiting).
  • Feeling sleepy.
  • Feeling confused.
  • Feeling constipated.

Please let your doctors know if you experience any of the above. Some side effects can be helped with other medication or alternative pain medication may need to be changed.

It is important to take pain medicine for the shortest possible time. If you want to try reducing your dose, you should discuss this with your doctor and bring the dose down slowly.

Many people find they can reduce their opioid dose without the pain increasing. As fewer side effects are experienced, quality and enjoyment of life can improve. All of this contributes to greater physical fitness.

What about addiction to pain killers?

Following surgery, many patients go home with an opioid pain medicine prescription, this can sometimes trigger addiction.

It is strongly recommended to only take opioids for the shortest possible length of time. Everyone prescribed any pain medication should have them reviewed by their prescriber at regular intervals.

Remember:

  • Opioid medicines should be used as little as possible, if at all, after surgery.
  • Nobody should need to take them for more than a week after an operation.
  • Addiction can develop after taking just a few of them.

People who are addicted to pain medicine can:

  • Feel out of control about how much medicine they take or how often they take it.
  • Crave the drug.
  • Continue to take the drug even when it has a negative effect on their day-to-day life, physical and/or mental health.

If you have been taking opioid pain medicine for more than a week, your body may have become used to the opioid medicine and you may experience symptoms of withdrawal (sweating, stomach cramps, diarrhoea, aching muscles) and the return of your pain if you:

  • Stop taking it too suddenly.
  • Lower the dose too quickly.
  • Run out of medicine.

You should not suddenly stop taking your opioid medicine but get advice from your doctor who will help you reduce the dose gradually and safely.

Is there anything else my prescriber needs to know?

  • If you are allergic to any medications.
  • If you are taking any other medication, including over the counter or herbal medication (sometimes different medications can interact with each other).
  • If you are pregnant or breastfeeding, or if you are planning to become pregnant in the near future.
  • If you have kidney and/or liver problems.
  • If you have or have previously had a history of excessive alcohol use, recreational drug use, or addiction to prescribed or over-the-counter medication.
  • If you have a condition called obstructive sleep apnoea - it may not be safe to take opioids with this condition.

It is important that you read the drug information leaflet provided with your medication on discharge. This includes more advice on driving and alcohol use along with your medicines.

Can I drink alcohol?

Taking alcohol and opioids together will cause sleepiness and reduce your ability to concentrate. When you first start taking opioids or when your dose is increased you should be more careful. When you are on a steady dose of opioid, you should be able to drink safe and modest amounts of alcohol without getting any extra unusual effects.

When you are taking opioids, you should not drink alcohol if you are going to drive or operate machinery.

Can I continue to drive?

UK law allows you to drive if you are taking opioid medicines. However, you are responsible for making sure you are safe to drive.

Because opioid medicines can make you feel sleepy, you should not drive or operate machinery until you see how it affects you. Your reactions and alertness will be affected. You should only consider driving regularly if you are confident that your concentration is not impaired. You should not drive if your dose has changed or if you feel unsafe. You do not have to inform the DVLA that you are starting an opioid. However, there may be other information about your illness that the DVLA needs to know.

Chronic/long term pain

If you have a history of chronic/long term pain and you are taking pain medicines for this at home before coming into hospital, your analgesia/pain relief will be discussed with your doctors/anaesthetist, and/or (if required) the acute pain team. 

How do I store opioids at home?

It is important that only you take the opioids prescribed for your pain.

Opioid medicines should be kept in their original containers and clearly labelled. They should be stored as the information leaflet given with the medication suggests, usually at room temperature in a dry place.

As with all medicines they should be stored safely out of the reach and sight of children.

What should I do with unused opioid medicines?

  • Return them to the pharmacist/pharmacy for safe disposal.
  • Do not share these medications with anyone, they are prescribed for you only.
  • Do not flush them down the toilet or throw them away.

Important final message

  • Everyone prescribed any pain relief medicines should have them reviewed by their prescriber at regular intervals.
  • Ideally pain relief medicines should be weaned and stopped safely as soon as able.
  • If this does not happen ask your medical team in hospital, or your GP.

© North Bristol NHS Trust. This edition published October 2024. Review due October 2027. NBT003158.

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See the impact we make across our hospitals and how you can be a part of it. 

It's okay to ask

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Find out about shared decision making at NBT. 

Community Participation Group

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Working with and learning from our communities to shape better care

Our Community Participation Group (CPG) works alongside NHS colleagues to ensure the lived experiences and needs of patients, carers and communities shape how services are planned and delivered.

This has been arranged by Bristol NHS Group, a partnership between North Bristol NHS Trust (NBT) and University Hospitals Bristol and Weston NHS Foundation Trust (UHBW) with the aim of delivering high quality care across Bristol, Weston, South Gloucestershire and the wider South West. The CPG brings together people with lived experience of using NHS services, including patients, carers, community leaders and representatives from voluntary and community organisations.

Recruitment of members to the CPG was supported by the BNSSG Voluntary, Community and Social Enterprise (VCSE) Alliance, helping ensure the group reflects the diversity of our local population.

Members meet regularly to share their perspectives on how services are developed and improved. Their insight helps ensure that changes support fair access to care, more consistent experiences and smoother pathways across the whole Group.

What the group does

CPG members help shape our services by:

  • Offering feedback on service proposals.
  • Advising on how changes may impact different groups.
  • Reviewing patient information to ensure it is clear and inclusive.
  • Making sure the voice and experiences of communities who are often underrepresented are heard and can influence decision making.

The CPG also plays an important role in supporting our Joint Clinical Strategy (JCS) which sets out our aspiration to deliver seamless, high quality, equitable and sustainable care for all our communities.

CPG impact

Since launching in September 2025, the CPG has supported several initiatives aiming to make services fairer, more joined up and easier to access. 

So far, this includes:

  • Providing feedback and insight based on lived experiences to support the development of our Joint Clinical Strategy Update 2026, which will be shared this Spring. 
  • Attending a relationship building event to create a supportive environment and strengthen the group’s identity.
  • Co-designing an engagement framework for the Group Clinical Services programme to help ensure future involvement is inclusive, meaningful and easy for people to take part in. 
  • The involvement of people with lived experience has brought a really positive energy to the work so far. Bringing together such a diverse group to share their perspectives at the highest levels of decision making is a new and encouraging way of working. This approach is helping ensure a broad range of voices and experiences shape changes from the very beginning.

Involving CPG voices at the highest levels of decision making and at the outset of any changes means we can ensure the services and care we provide reflect the needs of all our communities and the populations we serve. 

We will be sharing updates in this section and introducing more about our CPG members as the group continues to grow and its impact develops.

Get involved

Please note, we are not currently recruiting new members to the Community Participation Group. However, there are other opportunities to get involved through volunteering roles including Expert by Experience opportunities across our hospitals in Bristol and Weston:

What to expect in the Emergency Department

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Resus

Resus is for the most critically unwell patients with life or limb-threatening conditions.
 

Majors

Majors is for acutely unwell patients who require regular monitoring.

Minor Injuries Unit - See and Treat

See and Treat is our Minor Injuries Unit (MIU), and where most injuries get seen. 

The minor injury unit can see both children and adults. 

It can treat patients with minor injuries such as cuts, sprains, minor burns and suspected broken bones. 

We do not have a dedicated Minor Injuries team overnight, and all patients will be seen in the ED, along with the Majors and Resus patients. 

This means that after 1 am, patients with minor injuries may wait considerably longer than they would normally.

If you have a minor injury or illness overnight, you will be seen in order of clinical need alongside ambulance arrivals and emergency patients. 

At present, waiting times are much longer overnight, and you may be asked to come back the following morning, or to attend another suitable service instead. 

Other Minor Injuries units are at Yate MIU, Clevedon MIU and South Bristol Community Hospital.

ED Observation Unit (EDOU)

The ED Observation Unit is a seated assessment area for ambulatory patients who are well, but may need further observation and treatment.

If you are unlikely to require admission to hospital, and are waiting for results, need further treatment and/or observation, you will be transferred to our seated monitored waiting area (EDOU).

Occasionally, depending on the results of certain investigations, patients may need admission to a specialised ward from the EDOU.  

The EDOU also has capacity for two surgically expected patients, this means you may be referred directly by your GP to the EDOU, depending on your GP assessment.

Redirections

In the current climate, waiting times in the Emergency Department can be very long, and for many people, an emergency department is not the best place to be seen. 

The Senior Streaming Nurse may decide your condition does not need to be seen in the Emergency Department and may direct you elsewhere. 

This may happen if our team thinks your condition is not an emergency, or you have certain symptoms which mean you need to be seen by another healthcare provider.

You may be redirected to 111 (link to phoning 111 in the Emergency Department), local Minor Injuries Units (Yate and Clevedon), your GP, local pharmacies, Same Day Emergency Clinic (SDEC) (based at Gate 36, Level 1 of the hospital) or Bristol Children’s Hospital Emergency Department.

Welcome to Southmead Hospital Emergency Department Southmead Emergency Department

Urological Cancers

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Urological Cancers

This page has information about urological cancers and treatment at Bristol Urological Institute, and links to further information and support for patients with:

  • Bladder cancer.
  • Kidney Cancer.
  • Penile cancer.
  • Prostate cancer.
  • Testicular cancer.

During your time as a patient at Bristol Urological Institute you will meet different members of the team. This might include Clinical Nurse Specialists (CNSs), doctors, and surgeons.  

Find out more about the Urology Cancer CNS and Support Team: Urology Cancer Clinical Nurse Specialist and Support Team 

Some appointments and treatments are delivered across sites including Bristol Haematology and Oncology Centre  

Bladder Cancer

Around 10,000 people are diagnosed with bladder cancer each year. It often happens because harmful things like cigarette smoke can damage the bladder lining.   

The most common symptom is blood in the urine. If you have this see your GP immediately.  

The first step to treatment is finding out what stage your cancer is at. This is usually done with an operation called TURBT to remove the growth from the bladder to see how deep in the bladder wall it is (Day case TURBT (Transurethral Resection of the Bladder Tumour) You may also have a scan of the rest of the body. 

Treatment for bladder cancer depends on how deep it is in the bladder wall. If it is just inside the bladder it is called intravesical.  

If it involves the lining and muscles of the bladder this is called invasive. This is a serious diagnosis and often you will need both chemotherapy and surgery to treat it. 

Find out more about treatments for bladder cancer: 

Treatment for bladder can include surgery. Bristol Urological Institute has the most experienced surgeons in the country who provide robotic surgery for bladder cancer. Robotic assisted surgery allows smaller incisions (cuts), less blood loss, and less anaesthesia needed. This means patients recover far more quickly.

Our consultants Mr Koupparis and Mr Rowe were the first in the country to remove a patient’s bladder due to cancer and reconstruct a new bladder out of bowel using the Da Vinci robotic surgical platform. 

Kidney Cancer

Kidney cancer is also known as renal cancer and is most common in people over 60.  

Find out more about kidney cancer, symptoms, treatment, and recovery:

Penile cancer

Cancer of the penis is quite rare. If you have any symptoms you will need further tests like a biopsy, lymph node aspiration, and scans like a CT scan.  

Once we have the results of your tests, we will work out the right treatment with you. This may be a combination of treatments that could include: 

  • Surgery to remove the cancer, and possibly to reconstruct the penis.
  • Radiotherapy.
  • Chemotherapy.  

Find out more about penile cancer, symptoms, treatment, and recovery: 

Prostate cancer

Prostate cancer is the most common cancer in men in the UK. Slow-growing prostate cancer is more common and does not always cause symptoms or shorten life. It is often found on a routine blood screening. More aggressive prostate cancer can cause problems urinating (peeing) and can spread to other parts of the body like bones. 

At Bristol Urological Institute we have some of the most experienced prostate cancer specialists in the country. We work with our oncology colleagues and a team of specialist nurses. 

Find out more about treatments you may have for prostate cancer:

Find out more about prostate cancer, treatments, and support on the websites below:

Testicular cancer

Testicular cancer is most common in males aged 15-40. The risk of testicular cancer over your lifetime is roughly 1 in 250 (0.4%).

It has one of the highest cure rates of all cancers. More than 90% will be cured.  

Testicular cancer is often suspected if you find a lump. Not all lumps on the testicles are tumours, and not all tumours are malignant (cancerous).  If you find a lump, get it checked by your GP. Find out more about testicle swellings and lumps: Testicle lumps and swellings - NHS.

If your GP suspects your lump is a cancer, they will refer you for scans and blood tests. You may then meet a surgeon at Bristol Urological Institute to discuss removal of the testicle – this is called an orchidectomy.

Some important things to discuss with your surgeon

  • Your blood test results (tumour markers) before your operation
  • Prosthesis insertion.
  • Pre-operative sperm banking.

Most people will have surgery within the next 2 weeks, and you will usually go home on the same day (day case). You will be given all the information you need including when and where to go, and when to stop eating and drinking.

It is usually done under general anaesthetic (you will be asleep). When you wake up you will have a dressing on the wound on your groin. The stitches in the incision (cut) are usually dissolvable so don’t need to be removed.

Find out more about testicular cancer, symptoms, treatment, and recovery:

© North Bristol NHS Trust. This edition published Month 2025. Review due Month 2028. NBT003627.