Sample type: Serum

Test name: Vancomycin

Condition / Indication: Some requesters have found these assays to be of value in all patient groups treated for >48 hours while others consider them of value only in clinically defined sub groups of patients.

Advance warning: Not normally required during our core working hours (Mon – Fri 09:00 – 17:15). For samples originating outside of this trust, please contact the laboratory to discuss this assay being performed on Saturdays, Sundays and Bank Holidays when vancomycin samples can be assayed between 09:00 – 12:00.

Sample required: Approx. 1-2mL of separated serum (the minimum acceptable is 100µL). Samples may be sent by post. Transport time must be <4 weeks. Samples should be kept at 4°c if there is a delay in sending. Please contact laboratory if in doubt as sample integrity may be affected. Samples must be sealed and packed to conform to current regulations. Leaking samples may not be processed.

Timing of samples: We recommend a pre dose sample.

Test information required: • Patient name, sex and age
• Laboratory number
• Dosage, frequency and timing of samples; peak should be taken 1 hour after the end of the infusion to ensure the distribution phase has been completed.
• Clinical Summary
• Address for report
• Phone (fax if preferred) number for report or email address for an electronic copy
• Contact name
• Appropriate hazard warnings

Results: Results will be telephoned/faxed or emailed on the day of receipt for samples received between 9 am and 3 pm Monday to Friday and by 10.00 on a Saturday. A written confirmation report will be sent by post.

Reference range: Pre dose 10-15 mg/L but 15-20 mg/L in complicated infection or steady state during continuous infusion 20 - 25 mg/L

Container: Serum (Gold top)

Referred outside NBT for analysis? No

Discipline: Antimicrobial Reference Laboratory

Turnaround time: <1 day

Re-assay interval: 6-8 Days – Assuming initial results are within expected range.