Sample type: Serum

Test name: Vitamin B12 a.k.a. cobalamin, B12

Condition / Indication: Determination of B12 level. DO NOT send on patients on B12 therapy.

Special precautions & notes: None.

Reference range: B12 <100ng/L: likely deficiency, commence treatment; 100-145ng/L: possible deficiency. If clinical findings suggest deficiency consider a trial of therapy and assessment of response. Suggest consult guidelines in Remedy; 146-200ng/L: may still indicate deficiency. If strong clinical suspicion suggest discussion with a haematologist; 201-914ng/L: vitamin B12 deficiency not likely to be present; >914ng/L: High serum Vitamin B12. See Remedy for further guidance.

Container: Serum (Gold top)

Ideal volume (mL): 5 mL

Discipline: Clinical Biochemistry

Section: Automated Laboratory

Turnaround time: 3 days

remedy.bnssg.icb.nhs.uk/adults/haematology/vitamin-b12-interim-guidelines/